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06, 2021
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04, 2019
Paper of the Week: 11.04.2019: Breast Cancer Treatment, what to start, what to stop?
ruth brice2019-04-11T17:36:53+00:00Full Reference: Overall Survival with Fulvestrant plus Anastrozole in Metastatic Breast Cancer, Rita S. Mehta, Et al, N Engl J Med 2019; 380:1226-1234, DOI: 10.1056/NEJMoa1811714 Web link to Paper This week’s blog is brought to you by: Dr Tim Wilson Authors conclusion In this trial, we found that combination therapy with anastrozole plus fulvestrant significantly prolonged, as compared with treatment with anastrozole alone, the primary and secondary end points of progression-free survival (P=0.007) and long-term overall survival (P=0.03) when used as first-line therapy for hormone-receptor–positive metastatic breast cancer in postmenopausal women. 3VH - Implications for value Another promising treatment emerges for breast cancer. Not a cure, but one that prolongs survival from 42 to 49.8 months in women [...]
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04, 2019
Paper of the Week: 03.04.2019: Serving individuals and populations within integrated care systems
ruth brice2019-04-03T13:59:01+00:00Full reference: Moses, H., Matheson, D. H. M., & Poste, G. (2019). Serving Individuals and Populations Within Integrated Health Systems. JAMA. https://doi.org/10.1001/jama.2019.2929 WEB LINK TO PAPER This week’s blog is brought to you by: Dr Tim Wilson Authors conclusion "Despite their successes, a central question is whether the IHS model can meet the needs of all patients, particularly the aging population or patients with chronic illnesses who now account for 84% of health care spending and whose numbers are projected to triple by 2040" 3VH - Implications for value This article takes a look at integrated care in the US and contains many lessons for health services internationally. The first, unintended, lesson is that when communicating about [...]